Calcitriol granulomatous disease

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Sarcoidosis — The mechanism responsible for the abnormal calcium metabolism in granulomatous disease has been most completely evaluated in the most active metabolite of vitamin D) is the primary abnormality, although a calcitriol-induced increase in bone resorption may also contribute []. Tuberculosis, fungal granulomas, berylliosis, and lymphomas are other conditions that are associated with disorders of calcium metabolism. These abnormalities of calcium metabolism are due to dysregulated production of 1,(OH2)D3 (calcitriol) by activated macrophages trapped in pulmonary alveoli and granulomatous.

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Hypercalcemia secondary to granulomatous disease caused by the injection of methacrylate: a case series. Armando The four patients have as common elements the presence of moderate to severe renal insufficiency, suppressed PTH and elevated calcitriol levels for the degree of renal function. In the. Editorial from The New England Journal of Medicine — Calcitriol, Calcium, and Granulomatous Disease.

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