The NICE guideline on familial hypercholesterolaemia recommends that adults with the condition who have intolerance or contraindications to statins or ezetimibe should be offered referral to a specialist with expertise in this condition for consideration for treatment with a bile acid sequestrant, a fibrate or. Special care needed in patients with renal disease, as progressive increases in serum creatinine concentration or failure to follow dosage guidelines may result in myotoxicity (rhabdomyolysis); discontinue if myotoxicity suspected or creatine kinase concentration increases significantly. Manufacturer advises use with.
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NICE Pathways bring together all NICE guidance, quality standards and other NICE information on a specific topic. . Do not offer the combination of a bile acid sequestrant (anion exchange resin), fibrate, nicotinic NICE guideline on cardiovascular disease: risk assessment and reduction, including lipid. The NICE guideline on cardiovascular disease: risk assessment and reduction, including lipid The NICE technology appraisal guidance on ezetimibe for treating primary heterozygous-familial .. professionals should exercise caution when adding a fibrate or nicotinic acid to a statin because of.
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