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Não foram encontrados na literatura estudos de adequado rigor metodológico tais como Ensaios Clínicos Randomizados e Revisões Sistemáticas que comparassem o uso do Captopril ao uso do Enalapril, em pacientes diabéticos portadores de microalbuminúria e cujo desfecho principal seria evitar a Missing: ea. Amiga, leve seu marido ao cardiologista dele. Essa substituição de nada adiantaria, pois ambos os medicamentos têm o mesmo mecanismo de ação.
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